The vaccines against the coronavirus pandemic, in particular the mRNA vaccines, saved millions of lives. But the virus that the vaccines targeted in December 2020 is not the one we face today. While vaccines plus boosters offer protection against serious illness and death, the evolving virus seems to be one step ahead of the sheriff. Simply chasing each new variant with a booster is not a smart or sustainable strategy. What’s needed are next-generation vaccines that induce broader and more durable protection against known variants and the unknown, says Frida Ghitis. The new ideas face scientific, developmental, manufacturing, financial and regulatory hurdles, Ghitis says.
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